Across TCGA patient cohorts, KRTAP5-6 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP5-6-associated genes across cancer lineages are RN7SL726P, MIR6736, and UQCRBP2. Each is linked with KRTAP5-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-6-to-partner and partner-to-KRTAP5-6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-6→partner) and Y-score (partner→KRTAP5-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL726P →	+0.225	+3.488	<.001	<.001	3	1
SKCM	MIR6736 →	+0.469	+2.855	<.001	.009	3	1
COAD	UQCRBP2 →	+0.196	+4.321	<.001	.002	3	1
COAD	TBC1D26-AS1 →	+0.195	+4.624	<.001	.001	3	1
COAD	KIF3AP1 →	+0.389	+3.754	<.001	.008	3	1
COAD	BCAS2P1 →	+0.315	+3.951	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

Exploration

KRTAP5-6 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-6 data types