Across TCGA patient cohorts, KRTAP5-5 mutation is significantly associated with the RNA expression of many other genes, with 1,006 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP5-5-associated genes across cancer lineages are LINC01912, LINC02103, and SPATA31D3. Each is linked with KRTAP5-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-5-to-partner and partner-to-KRTAP5-5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-5→partner) and Y-score (partner→KRTAP5-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01912 →	+0.156	+4.452	<.001	<.001	3	2
UCEC	LINC02103 →	+0.127	+2.865	.001	.004	3	2
SKCM	SPATA31D3 →	+0.098	+4.098	<.001	.001	3	2
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	1
BRCA	LINC02729 →	+0.074	+7.731	<.001	.009	3	1
UCEC	SNURF →	+0.451	+3.711	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,006 associations by consensus.

Exploration

KRTAP5-5 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-5 data types