KRTAP5-4

Across TCGA cell cohorts, KRTAP5-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 268 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible KRTAP5-4-associated GO terms across cancer lineages are Protein targeting to ER, Cellular response to reactive oxygen species, and Negative regulation of TORC2 signaling. Each is linked with KRTAP5-4 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRTAP5-4-to-partner and partner-to-KRTAP5-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to ER grouped by KRTAP5-4-low versus KRTAP5-4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-4→partner) and Y-score (partner→KRTAP5-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein targeting to ER →	+0.100	+0.028	<.001	.007	3	4
PANCREAS	Cellular response to reactive oxygen species →	+0.071	+0.020	<.001	.004	3	4
BLOOD_Lymphoma	Negative regulation of TORC2 signaling →	-0.122	-0.007	.004	.004	3	3
BLOOD_Lymphoma	Axoneme assembly →	-0.036	-0.010	.004	.007	3	3
BLOOD_Lymphoma	Mitophagy →	+0.066	+0.013	<.001	.005	3	3
BLOOD_Lymphoma	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.108	+0.010	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 268 associations by consensus.

Protein targeting to ER by KRTAP5-4 expression — PANCREAS

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