KRTAP5-4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KRTAP5-4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KRTAP5-4-associated genes across cancer lineages are CD40LG. Each is linked with KRTAP5-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-4-to-partner and partner-to-KRTAP5-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD40LG grouped by KRTAP5-4-low versus KRTAP5-4-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-4→partner) and Y-score (partner→KRTAP5-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCCD40LG →+0.012+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD40LG by KRTAP5-4 expression — LUNG_SCLC

Box plot of CD40LG in KRTAP5-4-low vs KRTAP5-4-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration