KRTAP21-3

associated omics data
keratin associated protein 21-3Genealiases: []

Q-omics provides the consensus-scored KRTAP21-3 profile across patient tissues and cancer cell-line models. KRTAP21-3 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in LIHC. Additionally, KRTAP21-3 RNA expression shows 6,709 significant gene co-expression associations, with the highest sampling consensus in UCEC. Together, these results highlight LIHC, and UCEC as cancer lineages where KRTAP21-3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes KRTAP21-3 survival associations across molecular data types. KRTAP21-3 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
KRTAP21-3 data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier8LIHC (60)view →
This table ranks reproducible KRTAP21-3 RNA expression–survival associations across cancer types. High KRTAP21-3 expression shows unfavorable associations in LIHC, BLCA, READ, COAD and LGG, but favorable associations in ESCA. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for KRTAP21-3 RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCDFSTertileAll0.0430.527<.00160view →
BLCADFSTertileAll0.2380.629.00454view →
READDFSTertileAll0.1780.808<.00136view →
COADOSTertileIV0.0390.660<.00136view →
LGGOSTertileAll0.1940.830<.00124view →
ESCADFSTertileAll0.5650.271.01115view →
Pink = unfavorable, green = favorable. all 8 lineages →

KRTAP21-3-LIHC (DFS)

Kaplan–Meier survival curve for KRTAP21-3 RNA expression in LIHC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with KRTAP21-3 in patient tissues and cancer cell lines. In patient samples, KRTAP21-3 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set. In cancer cell lines, KRTAP21-3 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SKIN, while CRISPR and shRNA rows add functional-dependency signals in KIDNEY and STOMACH.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA6,709UCEC (2704)view →
Function (RNA)5,981STAD (5767)view →
Associated data typeStrength (# associated data)Lineage of highest associated data
CRISPR
CRISPR1,658SKIN (131)view →
shRNA1,262SKIN (101)view →
RNA
RNA52KIDNEY (41)view →
Mutation13STOMACH (11)view →