KRTAP21-3

Across TCGA cell cohorts, KRTAP21-3 RNA expression is significantly associated with the mutation status of many other genes, with 13 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible KRTAP21-3-associated genes across cancer lineages are SLC7A6, AGBL1, and MEFV. Each is linked with KRTAP21-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP21-3-to-partner and partner-to-KRTAP21-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC7A6 grouped by KRTAP21-3-low versus KRTAP21-3-high in KIDNEY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP21-3→partner) and Y-score (partner→KRTAP21-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	SLC7A6 →	+5.000	+0.366	.005	<.001	3	1
KIDNEY	AGBL1 →	+5.000	+0.366	.005	<.001	3	1
STOMACH	MEFV →	+5.285	+0.513	.003	<.001	3	1
STOMACH	PRMT7 →	+5.285	+0.513	.003	<.001	3	1
STOMACH	PDE5A →	+5.285	+0.513	.003	<.001	3	1
STOMACH	SLC38A6 →	+4.285	+0.385	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

SLC7A6 by KRTAP21-3 expression — KIDNEY

Explore this box plot interactively →