KRTAP11-1

Across TCGA cell cohorts, KRTAP11-1 RNA expression is significantly associated with the mutation status of many other genes, with 116 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KRTAP11-1-associated genes across cancer lineages are MAP3K5, TRIM11, and PTPN21. Each is linked with KRTAP11-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP11-1-to-partner and partner-to-KRTAP11-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP3K5 grouped by KRTAP11-1-low versus KRTAP11-1-high in OVARY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP11-1→partner) and Y-score (partner→KRTAP11-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MAP3K5 →	+5.807	+0.139	.001	<.001	3	2
SKIN	TRIM11 →	+5.415	+0.026	.004	<.001	3	2
OVARY	PTPN21 →	+3.807	+0.069	.009	<.001	3	2
BLOOD_Myeloma	HEPHL1 →	+3.754	+0.102	.002	.005	3	1
LUNG_SCLC	SHPRH →	+3.817	+0.037	.004	<.001	3	1
LUNG_SCLC	FAM47B →	+3.817	+0.028	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

MAP3K5 by KRTAP11-1 expression — OVARY

Explore this box plot interactively →