KRTAP11-1

Across TCGA pan-cancer cohorts, KRTAP11-1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated KRTAP11-1 data layer compared with 8 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher KRTAP11-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP11-1 expression acts as an unfavorable survival marker, although some lineages such as STAD and PRAD show a favorable association.

LIHC, READ, and BLCA are the cancer types where KRTAP11-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.471	0.798	<.001	117	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	102	view →
BLCA	DFS	Tertile	III,IV	0.224	0.456	<.001	93	view →
HNSC	DFS	Median	III,IV	0.150	0.447	<.001	67	view →
LUSC	DFS	Tertile	III,IV	0.010	0.754	<.001	54	view →
THCA	DFS	Tertile	II,III,IV	0.761	0.941	.004	48	view →
DLBC	OS	Tertile	II,III,IV	0.573	0.895	.011	45	view →
TGCT	DFS	Quartile	All	0.634	0.846	.005	44	view →
SCLC	DFS	Tertile	III,IV	0.236	0.591	.009	36	view →
ACC	OS	Tertile	II,III,IV	0.193	0.782	.001	33	view →
STAD	OS	Tertile	IV	0.805	0.283	.031	18	view →
COAD	OS	Tertile	IV	0.089	0.658	.012	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

KRTAP11-1–LIHC (OS)

Open the LIHC breakdown →