KRTAP11-1

Across TCGA pan-cancer cohorts, KRTAP11-1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of KRTAP11-1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KRTAP11-1 RNA is repressed in tumor relative to normal tissue. In most cancer types KRTAP11-1 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC, KIRC, and LUSC are the cancer types where KRTAP11-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP11-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	−0.805	.016	5	view →
KIRC	All	All	+0.012	.001	5	view →
LUSC	Male	All	+0.013	.029	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

KRTAP11-1–HNSC

Open the HNSC breakdown →