KRR1

Across TCGA patient cohorts, KRR1 mutation is significantly associated with the RNA expression of many other genes, with 2,066 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRR1-associated genes across cancer lineages are GJA1P1, RN7SL134P, and RNU6-365P. Each is linked with KRR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRR1-to-partner and partner-to-KRR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA1P1 grouped by KRR1-low versus KRR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRR1→partner) and Y-score (partner→KRR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GJA1P1 →	+0.199	+2.102	<.001	.006	3	2
UCEC	RN7SL134P →	+0.116	+2.336	.002	.006	3	2
LUAD	RNU6-365P →	+0.270	+7.930	<.001	.008	3	2
READ	RNU6-24P →	+0.582	+5.039	<.001	.008	3	2
UCEC	RNA5SP389 →	+0.729	+2.768	<.001	.001	3	2
UCEC	TRAJ57 →	+0.442	+2.444	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,066 associations by consensus.

GJA1P1 by KRR1 expression — UCEC

Explore this box plot interactively →