gap junction protein alpha 1 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored GJA1P1 profile across patient tissues and cancer cell-line models. GJA1P1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, GJA1P1 is differentially expressed in 7, with the highest sampling consensus in HNSC. Additionally, GJA1P1 RNA expression shows 14,906 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight MESO, HNSC, and KIRP as cancer lineages where GJA1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GJA1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GJA1P1 survival associations across molecular data types. GJA1P1 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GJA1P1 RNA expression–survival associations across cancer types. High GJA1P1 expression shows unfavorable associations in MESO, STAD, BLCA, LUSC, LGG and CHOL. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify MESO as the clearest survival context for GJA1P1 RNA expression.
This table summarizes GJA1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for GJA1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GJA1P1 shows lower tumor expression in THCA and STAD and higher tumor expression in HNSC, KIRC, BLCA and BRCA. The HNSC box plot shows higher GJA1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.233, t-test p < 0.001).
This table shows molecular features associated with GJA1P1 in patient tissues and cancer cell lines. In patient samples, GJA1P1 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
