GJA1P1

Across TCGA pan-cancer cohorts, GJA1P1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GJA1P1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher GJA1P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GJA1P1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and ESCA show a favorable association.

MESO, STAD, and BLCA are the cancer types where GJA1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.275	0.486	.001	83	view →
STAD	DFS	Tertile	All	0.438	0.648	<.001	80	view →
BLCA	DFS	Median	II,III,IV	0.273	0.406	.007	52	view →
LGG	DFS	Median	All	0.306	0.447	<.001	37	view →
LUSC	DFS	Tertile	III,IV	0.330	1.000	<.001	37	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	33	view →
KIRP	OS	Quartile	II,III,IV	0.159	0.733	.008	26	view →
TGCT	DFS	Median	II,III,IV	0.732	1.000	.020	20	view →
SARC	DFS	Tertile	All	0.237	0.496	.003	18	view →
LIHC	DFS	Quartile	All	0.331	0.471	.020	17	view →
PAAD	OS	Quartile	II,III,IV	0.584	0.282	.003	17	view →
UCEC	DFS	Quartile	All	0.783	0.860	.030	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GJA1P1–MESO (OS)

Open the MESO breakdown →