KMT2E-AS1

Across TCGA patient cohorts, KMT2E-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,072 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KMT2E-AS1-associated proteins across cancer lineages are RAD21, MEPCE, and SIN3A. Each is linked with KMT2E-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KMT2E-AS1-to-partner and partner-to-KMT2E-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMT2E-AS1 versus RAD21 in GBM, with a Pearson correlation of 0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT2E-AS1→partner) and Y-score (partner→KMT2E-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAD21 →	+0.286	+0.277	.006	.003	3	6
LSCC	MEPCE →	+0.439	+0.686	<.001	<.001	3	5
LSCC	SIN3A →	+0.214	+0.399	<.001	<.001	3	5
HNSC	ZKSCAN1 →	+0.404	+0.933	<.001	.001	3	4
GBM	NELFA →	+0.279	+0.335	<.001	<.001	3	4
LSCC	HDLBP →	-0.285	-0.538	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,072 associations by consensus.

KMT2E-AS1 vs RAD21 — GBM

Explore this scatter interactively →