KLKB1

Across TCGA cell cohorts, KLKB1 RNA expression is significantly associated with the RNA expression of many other genes, with 3,447 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLKB1-associated genes across cancer lineages are CYP4V2, PJVK, and FAM149A. Each is linked with KLKB1 in more than 13 cancer types. Because this analysis shows association rather than direction, both KLKB1-to-partner and partner-to-KLKB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLKB1 versus CYP4V2 in KIDNEY, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLKB1→partner) and Y-score (partner→KLKB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	CYP4V2 →	+2.095	+0.534	<.001	.001	3	14
LARGE_INTESTINE	PJVK →	+1.192	+0.454	<.001	<.001	3	5
KIDNEY	FAM149A →	+2.732	+0.529	<.001	.001	3	5
KIDNEY	CCDC30 →	+1.058	+0.598	<.001	.002	2	5
LARGE_INTESTINE	KATNAL2 →	+1.438	+0.402	<.001	.001	3	4
OVARY	CFAP70 →	+0.875	+0.178	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,447 associations by consensus.

KLKB1 vs CYP4V2 — KIDNEY

Explore this scatter interactively →