KLHL24

Across TCGA patient cohorts, KLHL24 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,018 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL24-associated proteins across cancer lineages are DCUN1D1, EPS15_S221, and SRRT. Each is linked with KLHL24 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLHL24-to-partner and partner-to-KLHL24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL24 versus DCUN1D1 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL24→partner) and Y-score (partner→KLHL24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DCUN1D1 →	+0.476	+1.151	<.001	<.001	3	6
HNSC	EPS15_S221 →	-0.446	-1.112	<.001	<.001	3	6
LSCC	SRRT →	+0.221	+0.824	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.295	+0.543	<.001	<.001	3	5
HNSC	CHAMP1 →	+0.310	+0.893	<.001	.001	3	5
HNSC	NUCKS1_S214 →	+0.414	+1.075	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,018 associations by consensus.

KLHL24 vs DCUN1D1 — LSCC

Explore this scatter interactively →