KLF10

Across TCGA patient cohorts, KLF10 mutation is significantly associated with the RNA expression of many other genes, with 1,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLF10-associated genes across cancer lineages are LINC01899, MIA-RAB4B, and MBD3L4. Each is linked with KLF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF10-to-partner and partner-to-KLF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01899 grouped by KLF10-low versus KLF10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF10→partner) and Y-score (partner→KLF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01899 →	+0.084	+2.019	.001	.008	3	2
UCEC	MIA-RAB4B →	+0.053	+1.711	.007	.009	3	2
HNSC	MBD3L4 →	+0.069	+7.954	<.001	.008	3	2
COAD	RNU6-628P →	+0.448	+4.792	.003	.003	3	2
SKCM	NDUFB4P5 →	+0.081	+4.884	<.001	.004	3	2
UCEC	PINCR →	+0.310	+2.285	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,621 associations by consensus.

LINC01899 by KLF10 expression — UCEC

Explore this box plot interactively →