KIF15

Across TCGA patient cohorts, KIF15 mutation is significantly associated with the RNA expression of many other genes, with 4,039 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF15-associated genes across cancer lineages are TP53TG3GP, FAM96AP1, and GAPDHP19. Each is linked with KIF15 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF15-to-partner and partner-to-KIF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53TG3GP grouped by KIF15-low versus KIF15-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF15→partner) and Y-score (partner→KIF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TP53TG3GP →	+0.426	+3.962	.001	.005	3	3
HNSC	FAM96AP1 →	+0.041	+4.468	<.001	.006	3	3
HNSC	GAPDHP19 →	+0.066	+3.473	<.001	.005	3	3
UCEC	EDC3 →	+0.203	+1.462	.005	<.001	3	3
UCEC	PITPNB →	+0.337	+1.769	<.001	<.001	3	3
UCEC	KMT5A →	+0.408	+1.451	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,039 associations by consensus.

TP53TG3GP by KIF15 expression — LUAD

Explore this box plot interactively →