KIF15

Across TCGA pan-cancer cohorts, KIF15 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of KIF15’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where KIF15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIF15 is over-expressed in tumor.

BLCA, LUAD, and KIRP are the cancer types where KIF15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIF15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+2.562	<.001	12	view →
LUAD	Male	III,IV	+2.413	<.001	11	view →
KIRP	All	III,IV	+1.007	<.001	11	view →
STAD	Female	All	+2.091	<.001	10	view →
KIRC	Male	IV	+0.825	<.001	10	view →
LIHC	Female	II,III,IV	+1.160	<.001	9	view →
HNSC	Male	All	+1.100	<.001	9	view →
COAD	Male	All	+1.038	<.001	9	view →
UCEC	All	III,IV	+3.076	<.001	8	view →
LUSC	Male	II,III,IV	+2.567	<.001	8	view →
BRCA	All	III,IV	+1.884	<.001	6	view →
CHOL	Male	All	+2.288	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

KIF15–BLCA

Open the BLCA breakdown →