KIF14

Across TCGA patient cohorts, KIF14 protein abundance is significantly associated with the RNA expression of many other genes, with 14,845 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF14-associated genes across cancer lineages are TTK, CENPA, and NEK2. Each is linked with KIF14 in more than 6 cancer types. Because this analysis shows association rather than direction, both KIF14-to-partner and partner-to-KIF14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF14 versus TTK in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF14→partner) and Y-score (partner→KIF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TTK →	+1.398	+1.016	<.001	<.001	3	7
UCEC	CENPA →	+1.210	+0.418	<.001	<.001	3	7
OV	NEK2 →	+1.137	+0.476	<.001	.001	3	7
UCEC	CENPF →	+1.328	+0.323	<.001	.005	3	7
UCEC	TOP2A →	+1.197	+0.329	<.001	.003	3	7
OV	CCNA2 →	+1.044	+0.601	.006	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,845 associations by consensus.

KIF14 vs TTK — GBM

Explore this scatter interactively →