KIAA1549

Across TCGA cell cohorts, KIAA1549 mutation is significantly associated with the mutation status of many other genes, with 4,669 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1549-associated genes across cancer lineages are TRRAP, MMP25, and SYNE1. Each is linked with KIAA1549 in more than 7 cancer types. Because this analysis shows association rather than direction, both KIAA1549-to-partner and partner-to-KIAA1549 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRRAP grouped by KIAA1549-low versus KIAA1549-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1549→partner) and Y-score (partner→KIAA1549) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TRRAP →	+3.022	+4.321	<.001	<.001	1	8
BLOOD_Leukemia	MMP25 →	+2.452	+2.093	.003	.003	1	7
SOFT_TISSUE	SYNE1 →	+2.199	+2.900	.002	.002	1	7
PANCREAS	LAMB4 →	+5.115	+5.115	.005	.005	1	6
OVARY	UBR4 →	+2.510	+2.510	.004	.004	1	6
URINARY_TRACT	DYNC1H1 →	+3.152	+4.228	<.001	<.001	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,669 associations by consensus.

TRRAP by KIAA1549 expression — STOMACH

Explore this box plot interactively →