KIAA0319L

Across TCGA patient cohorts, KIAA0319L mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0319L-associated genes across cancer lineages are ASNS, GSK3-a-b, and STAT5a. Each is linked with KIAA0319L in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0319L-to-partner and partner-to-KIAA0319L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by KIAA0319L-low versus KIAA0319L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0319L→partner) and Y-score (partner→KIAA0319L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.472	+1.678	<.001	.021	3	3
BLCA	GSK3-a-b →	+0.198	+3.000	.019	.036	3	2
BLCA	STAT5a →	+0.692	+3.000	.006	.034	3	2
UCEC	Di-Ras3 →	-0.177	-2.986	<.001	<.001	3	2
UCEC	N-Ras →	-0.104	-1.427	.012	.024	3	2
UCEC	p62 Lck ligand →	+0.276	+3.459	.014	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ASNS by KIAA0319L expression — UCEC

Explore this box plot interactively →