KIAA0319L

Across TCGA cell cohorts, KIAA0319L mutation is significantly associated with the RNA expression of many other genes, with 134 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0319L-associated genes across cancer lineages are C2CD4B, LCE1C, and SLC5A8. Each is linked with KIAA0319L in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0319L-to-partner and partner-to-KIAA0319L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2CD4B grouped by KIAA0319L-low versus KIAA0319L-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0319L→partner) and Y-score (partner→KIAA0319L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	C2CD4B →	+0.034	+5.044	.002	.001	3	2
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CFHR2 →	+0.395	+5.539	<.001	.003	3	1
CNS	RETN →	+0.116	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 134 associations by consensus.

C2CD4B by KIAA0319L expression — CNS

Explore this box plot interactively →