KIAA0232

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0232 mutation is significantly associated with the RNA expression of many other genes, with 4,159 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0232-associated genes across cancer lineages are CRK, IL22RA1, and CD27-AS1. Each is linked with KIAA0232 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0232-to-partner and partner-to-KIAA0232 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRK grouped by KIAA0232-low versus KIAA0232-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0232→partner) and Y-score (partner→KIAA0232) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCRK →+0.267+1.384.003<.00133
COADIL22RA1 →-0.869-3.700<.001.00133
UCECCD27-AS1 →-0.446-1.705<.001.00333
UCECSNORD62A →+0.264+1.163.002.00533
BRCAMIR6780B →+0.272+2.856.004.00632
LIHCRNA5SP393 →+0.336+5.355<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

CRK by KIAA0232 expression — UCEC

Box plot of CRK in KIAA0232-low vs KIAA0232-high samples in UCEC.

Explore this box plot interactively →

Exploration