Q-omics provides the consensus-scored KIAA0087 profile across patient tissues and cancer cell-line models. KIAA0087 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in ESCA. Among the 18 cancer types available for tumor–normal comparison, KIAA0087 is differentially expressed in 7, with the highest sampling consensus in LUSC. Additionally, KIAA0087 RNA expression shows 14,867 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight ESCA, LUSC, and KIRP as cancer lineages where KIAA0087 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KIAA0087 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KIAA0087 survival associations across molecular data types. KIAA0087 RNA expression shows survival associations in the most cancer types (22), followed by mass-spec protein abundance (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KIAA0087 RNA expression–survival associations across cancer types. High KIAA0087 expression shows unfavorable associations in THCA, UVM and LAML, but favorable associations in ESCA, LUAD and ACC. The ESCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify ESCA as the clearest survival context for KIAA0087 RNA expression.
This table summarizes KIAA0087 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7, while mass-spec protein shows differences in 4. The strongest signals are observed in LUSC for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for KIAA0087. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KIAA0087 shows lower tumor expression in LUSC, LUAD, BRCA and UCEC and higher tumor expression in KIRC and PRAD. The LUSC box plot shows higher KIAA0087 RNA expression in normal versus tumor tissue (log2 FC = −0.249, t-test p < 0.001).
This table shows molecular features associated with KIAA0087 in patient tissues and cancer cell lines. In patient samples, KIAA0087 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set. In cancer cell lines, KIAA0087 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in NCI60_ALL.
