KIAA0087

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0087 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0087-associated genes across cancer lineages are AQP7P3, RNA5SP477, and RNY4P24. Each is linked with KIAA0087 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0087-to-partner and partner-to-KIAA0087 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P3 grouped by KIAA0087-low versus KIAA0087-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0087→partner) and Y-score (partner→KIAA0087) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAQP7P3 →+0.057+3.997<.001.00931
UCECRNA5SP477 →+0.878+3.330.009.00931
UCECRNY4P24 →+0.359+3.198<.001.00931
UCECRNA5SP358 →+0.456+3.198<.001.00931
UCECRNU6-1155P →+0.221+5.475<.001.00131
UCECRNU6-1284P →+0.429+3.450.005.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

AQP7P3 by KIAA0087 expression — UCEC

Box plot of AQP7P3 in KIAA0087-low vs KIAA0087-high samples in UCEC.

Explore this box plot interactively →

Exploration