KIAA0087

Across TCGA pan-cancer cohorts, KIAA0087 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated KIAA0087 data layer compared with 3 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher KIAA0087 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA0087 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

ESCA, THCA, and UVM are the cancer types where KIAA0087 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	All	0.715	0.442	<.001	87	view →
THCA	OS	Tertile	IV	0.547	0.893	.003	44	view →
UVM	OS	Median	III,IV	0.241	0.768	.014	33	view →
LAML	DFS	Quartile	All	0.423	0.695	.001	30	view →
LUAD	OS	Tertile	All	0.746	0.630	.005	29	view →
ACC	OS	Tertile	III,IV	0.902	0.340	.017	20	view →
KIRP	DFS	Median	All	0.918	0.615	.005	18	view →
CHOL	DFS	Median	IV	0.251	0.794	.010	17	view →
COAD	OS	Tertile	III,IV	0.871	0.707	.013	13	view →
TGCT	OS	Tertile	All	0.935	1.000	.034	12	view →
READ	DFS	Tertile	IV	0.360	0.630	.007	12	view →
THYM	OS	Tertile	All	1.000	0.729	.006	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

KIAA0087–ESCA (DFS)

Open the ESCA breakdown →