Across TCGA patient cohorts, KHDC3L RNA expression is significantly associated with the go_rna of many other GO terms, with 7,048 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KHDC3L-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Mitochondrial gene expression, and Nucleotide-excision repair. Each is linked with KHDC3L in more than 15 cancer types. Because this analysis shows association rather than direction, both KHDC3L-to-partner and partner-to-KHDC3L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC3L→partner) and Y-score (partner→KHDC3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of RNA splicing →	+0.073	+0.206	<.001	<.001	3	16
STAD	Mitochondrial gene expression →	+0.069	+0.238	<.001	<.001	3	15
STAD	Nucleotide-excision repair →	+0.052	+0.203	<.001	<.001	3	15
STAD	Positive regulation of stem cell population maintenance →	+0.066	+0.207	<.001	<.001	3	15
STAD	Peptidyl-lysine modification →	+0.063	+0.228	<.001	<.001	3	15
STAD	Virion assembly →	+0.059	+0.229	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

Exploration

KHDC3L survival (RNA) · tumor vs normal (RNA) · all KHDC3L data types