KHDC3L

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KHDC3L mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KHDC3L-associated genes across cancer lineages are Fibronectin, Ku80, and p70-S6K_pT389. Each is linked with KHDC3L in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDC3L-to-partner and partner-to-KHDC3L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC3L→partner) and Y-score (partner→KHDC3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFibronectin →-0.359-2.990.038.03632
SKCMKu80 →+0.320+3.459.009.00532
UCECp70-S6K_pT389 →-0.240-2.990.016.03632
UCECShc_pY317 →-0.211-3.000.008.03632
SKCMACC_pS79 →+0.282+2.700.029.00632
SKCMNF-kB-p65_pS536 →+0.410+2.000.019.03132
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration