Across TCGA cell cohorts, KHDC3L RNA expression is significantly associated with the mutation status of many other genes, with 641 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KHDC3L-associated genes across cancer lineages are LYST, VWA8, and DNAH11. Each is linked with KHDC3L in more than 2 cancer types. Because this analysis shows association rather than direction, both KHDC3L-to-partner and partner-to-KHDC3L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC3L→partner) and Y-score (partner→KHDC3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	LYST →	+4.035	+0.028	.003	<.001	3	3
OVARY	VWA8 →	+2.974	+0.055	.006	<.001	3	3
LUNG_NSCLC_LUAD	DNAH11 →	+1.478	+0.012	.007	.004	3	3
BLOOD_Leukemia	ROBO2 →	+2.774	+0.100	<.001	.001	3	3
SOFT_TISSUE	PXDNL →	+4.450	+0.060	<.001	<.001	3	2
OESOPHAGUS	CTNND2 →	+2.432	+0.037	.008	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 641 associations by consensus.

Exploration

KHDC3L survival (RNA) · tumor vs normal (RNA) · all KHDC3L data types