Q-omics provides the consensus-scored KDM7A-DT profile across patient tissues and cancer cell-line models. KDM7A-DT expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, KDM7A-DT is differentially expressed in 12, with the highest sampling consensus in THCA. Additionally, KDM7A-DT RNA expression shows 18,351 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and THCA as cancer lineages where KDM7A-DT shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KDM7A-DT — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KDM7A-DT survival associations across molecular data types. KDM7A-DT RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KDM7A-DT RNA expression–survival associations across cancer types. High KDM7A-DT expression shows unfavorable associations in UVM, BLCA, KICH, COAD and GBM, but favorable associations in SKCM. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for KDM7A-DT RNA expression.
This table summarizes KDM7A-DT tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for KDM7A-DT. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KDM7A-DT shows lower tumor expression in THCA and KIRC and higher tumor expression in UCEC, LIHC, LUSC and PAAD. The THCA box plot shows higher KDM7A-DT RNA expression in normal versus tumor tissue (log2 FC = −0.757, t-test p < 0.001).
This table shows molecular features associated with KDM7A-DT in patient tissues and cancer cell lines. In patient samples, KDM7A-DT shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
