KCNU1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNU1 mutation is significantly associated with the RNA expression of many other genes, with 1,124 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNU1-associated genes across cancer lineages are TREH, OXT, and DCAF11. Each is linked with KCNU1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNU1-to-partner and partner-to-KCNU1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNU1→partner) and Y-score (partner→KCNU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaTREH →+0.023+4.807<.001.00632
BLOOD_LymphomaOXT →+0.044+3.523<.001.00932
LUNG_NSCLC_LUADDCAF11 →+0.654+3.206.002.00632
LARGE_INTESTINESEPSECS →+0.706+3.628<.001<.00132
LUNG_NSCLC_LUADPPTC7 →+0.630+3.206<.001.00632
LUNG_NSCLC_LUADKHDC3L →+0.026+2.799<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,124 associations by consensus.

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