KCNK16

Across TCGA patient cohorts, KCNK16 mutation is significantly associated with the RNA expression of many other genes, with 4,889 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNK16-associated genes across cancer lineages are TMSB4XP3, USP9YP2, and LINC01078. Each is linked with KCNK16 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNK16-to-partner and partner-to-KCNK16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMSB4XP3 grouped by KCNK16-low versus KCNK16-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK16→partner) and Y-score (partner→KCNK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TMSB4XP3 →	+0.729	+3.810	.001	.005	3	3
UCEC	USP9YP2 →	+0.013	+4.606	<.001	.001	3	3
BLCA	LINC01078 →	+0.115	+4.899	<.001	.005	3	3
BLCA	NDUFB8P1 →	+0.125	+4.497	<.001	.009	3	2
BLCA	RN7SL785P →	+0.240	+5.376	<.001	.001	3	2
CESC	LINC01490 →	+0.050	+5.729	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,889 associations by consensus.

TMSB4XP3 by KCNK16 expression — COAD

Explore this box plot interactively →