KCNH1-IT1

Across TCGA patient cohorts, KCNH1-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,060 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNH1-IT1-associated proteins across cancer lineages are WNK2_S1862, SLC39A6, and PLCB2. Each is linked with KCNH1-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNH1-IT1-to-partner and partner-to-KCNH1-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNH1-IT1 versus WNK2_S1862 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH1-IT1→partner) and Y-score (partner→KCNH1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WNK2_S1862 →	+1.049	+0.676	<.001	.001	3	3
BRCA	SLC39A6 →	+0.517	+0.850	<.001	<.001	3	3
LSCC	PLCB2 →	-0.367	-0.782	<.001	<.001	3	3
BRCA	TCEAL3 →	+0.772	+0.637	<.001	<.001	3	3
GBM	TRIP4 →	-0.277	-0.955	.001	<.001	3	3
GBM	PARVB →	-0.438	-0.776	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,060 associations by consensus.

KCNH1-IT1 vs WNK2_S1862 — LSCC

Explore this scatter interactively →