KATNB1

Across TCGA cell cohorts, KATNB1 mutation is significantly associated with the mutation status of many other genes, with 822 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KATNB1-associated genes across cancer lineages are WDR81, MAP7D1, and LNPK. Each is linked with KATNB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KATNB1-to-partner and partner-to-KATNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR81 grouped by KATNB1-low versus KATNB1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNB1→partner) and Y-score (partner→KATNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WDR81 →	+2.285	+3.364	.006	.006	1	3
UPPER_AERODIGESTIVE_TRACT	MAP7D1 →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	LNPK →	+5.392	+5.392	.004	.004	1	2
BLOOD_Leukemia	GABRB2 →	+4.870	+4.560	<.001	<.001	1	2
UPPER_AERODIGESTIVE_TRACT	FOXO1 →	+5.392	+5.392	.004	.004	1	2
UPPER_AERODIGESTIVE_TRACT	SORBS2 →	+5.392	+5.392	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 822 associations by consensus.

WDR81 by KATNB1 expression — BLOOD_Leukemia

Explore this box plot interactively →