KANTR

Across TCGA patient cohorts, KANTR mutation is significantly associated with the RNA expression of many other genes, with 782 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KANTR-associated genes across cancer lineages are SNORA108, RNU6-342P, and ATP8B5P. Each is linked with KANTR in more than 1 cancer types. Because this analysis shows association rather than direction, both KANTR-to-partner and partner-to-KANTR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA108 grouped by KANTR-low versus KANTR-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANTR→partner) and Y-score (partner→KANTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORA108 →	+0.359	+3.466	<.001	.003	3	2
HNSC	RNU6-342P →	+0.435	+5.241	<.001	.007	3	1
UCEC	ATP8B5P →	+0.185	+3.747	<.001	<.001	3	1
UCEC	PCBP1-AS1 →	+0.588	+2.201	<.001	.009	3	1
UCEC	TMEM150B →	+0.755	+3.491	<.001	.002	3	1
UCEC	ZNF816 →	+0.573	+3.202	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 782 associations by consensus.

SNORA108 by KANTR expression — UCEC

Explore this box plot interactively →