KANTR

Across TCGA pan-cancer cohorts, KANTR RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of KANTR’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where KANTR RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KANTR is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

LIHC, BLCA, and KIRC are the cancer types where KANTR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KANTR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	II,III,IV	+0.217	.001	7	view →
BLCA	Female	III,IV	+0.462	.001	5	view →
KIRC	All	All	+0.178	.004	5	view →
THCA	Female	II,III,IV	−0.528	<.001	4	view →
READ	Male	All	+0.476	.021	4	view →
CHOL	Male	All	+0.671	.007	3	view →
LUSC	All	II,III,IV	+0.285	.006	3	view →
COAD	Male	II,III,IV	+0.210	.043	2	view →
KICH	Female	All	−0.332	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

KANTR–LIHC

Open the LIHC breakdown →