KANTR

Across TCGA pan-cancer cohorts, KANTR RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated KANTR data layer compared with 2 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher KANTR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KANTR expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

KICH, MESO, and BLCA are the cancer types where KANTR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.257	1.000	.001	51	view →
MESO	DFS	Median	IV	0.189	0.521	.002	45	view →
BLCA	OS	Median	All	0.772	0.661	.002	42	view →
COAD	DFS	Median	All	0.333	0.616	.001	34	view →
KIRC	DFS	Median	All	0.751	0.860	<.001	30	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	30	view →
THCA	OS	Median	All	0.963	1.000	.012	28	view →
PAAD	DFS	Quartile	All	0.418	0.218	.002	21	view →
LIHC	DFS	Tertile	All	0.477	0.599	.015	18	view →
KIRP	DFS	Quartile	All	0.775	0.951	.003	15	view →
THYM	DFS	Median	III,IV	1.000	0.480	.010	14	view →
ACC	DFS	Median	All	0.300	0.601	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

KANTR–KICH (DFS)

Open the KICH breakdown →