ITGB1BP2

Across TCGA patient cohorts, ITGB1BP2 mutation is significantly associated with the RNA expression of many other genes, with 1,708 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGB1BP2-associated genes across cancer lineages are RNU6-158P, DNAJA1P1, and RNU6-752P. Each is linked with ITGB1BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGB1BP2-to-partner and partner-to-ITGB1BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-158P grouped by ITGB1BP2-low versus ITGB1BP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1BP2→partner) and Y-score (partner→ITGB1BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-158P →	+0.687	+5.122	<.001	.004	3	2
LUAD	DNAJA1P1 →	+0.034	+5.000	<.001	.003	3	2
BLCA	RNU6-752P →	+0.266	+4.562	<.001	.006	3	2
UCEC	HSPE1-MOB4 →	+0.121	+1.992	.008	.003	3	1
UCEC	CCL5 →	+1.248	+2.238	<.001	.006	3	1
UCEC	IGKV1OR2-6 →	+0.633	+2.082	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,708 associations by consensus.

RNU6-158P by ITGB1BP2 expression — COAD

Explore this box plot interactively →