ITGB1BP2

Across TCGA pan-cancer cohorts, ITGB1BP2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ITGB1BP2 data layer compared with 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ITGB1BP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ITGB1BP2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.

COAD, ACC, and UVM are the cancer types where ITGB1BP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.617	0.784	<.001	98	view →
ACC	DFS	Median	All	0.380	0.764	<.001	88	view →
UVM	DFS	Tertile	All	0.419	0.856	<.001	63	view →
KIRP	DFS	Quartile	All	0.442	0.809	.001	56	view →
KIRC	DFS	Tertile	All	0.539	0.692	<.001	55	view →
SKCM	OS	Quartile	II,III,IV	0.472	0.276	.006	48	view →
CHOL	DFS	Median	II,III,IV	0.136	0.620	.001	39	view →
BRCA	DFS	Tertile	IV	0.303	0.800	.001	37	view →
THCA	DFS	Tertile	II,III,IV	0.877	0.973	.003	15	view →
READ	OS	Median	All	0.867	0.963	.008	13	view →
UCEC	DFS	Median	All	0.870	0.921	.013	12	view →
MESO	OS	Median	II,III,IV	0.499	0.630	.008	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ITGB1BP2–COAD (DFS)

Open the COAD breakdown →