RNU6-158P

Q-omics provides the consensus-scored RNU6-158P profile across patient tissues and cancer cell-line models. RNU6-158P expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNU6-158P RNA expression shows 5,790 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where RNU6-158P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-158P survival associations across molecular data types. RNU6-158P RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-158P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	HNSC (42)	view →

This table ranks reproducible RNU6-158P RNA expression–survival associations across cancer types. High RNU6-158P expression shows unfavorable associations in LUAD, SKCM and PCPG, but favorable associations in HNSC, PAAD and ESCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .011). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU6-158P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.791	0.305	.011	42	view →
LUAD	DFS	Tertile	IV	0.109	0.714	.001	36	view →
PAAD	DFS	Tertile	All	0.763	0.247	.003	36	view →
SKCM	OS	Tertile	All	0.532	0.791	.008	27	view →
PCPG	OS	Tertile	All	0.900	0.992	.003	24	view →
ESCA	DFS	Tertile	III,IV	0.648	0.266	.023	18	view →

Pink = unfavorable, green = favorable. all 9 lineages →

RNU6-158P-HNSC (DFS)

Explore this curve interactively →