RNU6-158P

Across TCGA pan-cancer cohorts, RNU6-158P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-158P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-158P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-158P expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, PAAD, and LUAD are the cancer types where RNU6-158P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.791	0.305	.011	42	view →
PAAD	DFS	Tertile	All	0.763	0.247	.003	36	view →
LUAD	DFS	Tertile	IV	0.109	0.714	.001	36	view →
SKCM	OS	Tertile	All	0.532	0.791	.008	27	view →
PCPG	OS	Tertile	All	0.900	0.992	.003	24	view →
ESCA	DFS	Tertile	III,IV	0.648	0.266	.023	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.761	.014	9	view →
KIRP	OS	Tertile	All	1.000	0.868	.023	6	view →
LGG	OS	Quartile	All	0.271	0.496	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-158P–HNSC (DFS)

Open the HNSC breakdown →