IQCB1

Across TCGA patient cohorts, IQCB1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,415 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IQCB1-associated genes across cancer lineages are RAD51AP1, SLC41A3, and TOPBP1. Each is linked with IQCB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both IQCB1-to-partner and partner-to-IQCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCB1 versus RAD51AP1 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCB1→partner) and Y-score (partner→IQCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAD51AP1 →	+0.789	+0.266	.001	.001	3	3
LSCC	SLC41A3 →	+0.416	+0.249	<.001	.004	3	3
LSCC	TOPBP1 →	+0.674	+0.363	<.001	<.001	3	3
LSCC	RFC4 →	+0.602	+0.308	<.001	<.001	3	3
LSCC	IFT122 →	+0.538	+0.370	.001	.002	3	3
LSCC	ACAD9 →	+0.563	+0.421	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,415 associations by consensus.

IQCB1 vs RAD51AP1 — BRCA

Explore this scatter interactively →