Q-omics provides the consensus-scored INTS6-AS1 profile across patient tissues and cancer cell-line models. INTS6-AS1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in PAAD. Among the 18 cancer types available for tumor–normal comparison, INTS6-AS1 is differentially expressed in 14, with the highest sampling consensus in KICH. Additionally, INTS6-AS1 RNA expression shows 18,854 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight PAAD, KICH, and UVM as cancer lineages where INTS6-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for INTS6-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes INTS6-AS1 survival associations across molecular data types. INTS6-AS1 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible INTS6-AS1 RNA expression–survival associations across cancer types. High INTS6-AS1 expression shows unfavorable associations in ACC, COAD, OV, UVM and LIHC, but favorable associations in PAAD. The PAAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify PAAD as the clearest survival context for INTS6-AS1 RNA expression.
This table summarizes INTS6-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for INTS6-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. INTS6-AS1 shows lower tumor expression in KICH, KIRP and UCEC and higher tumor expression in LIHC, HNSC and COAD. The KICH box plot shows higher INTS6-AS1 RNA expression in normal versus tumor tissue (log2 FC = −0.741, t-test p < 0.001).
This table shows molecular features associated with INTS6-AS1 in patient tissues and cancer cell lines. In patient samples, INTS6-AS1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
