INTS6-AS1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, INTS6-AS1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated INTS6-AS1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher INTS6-AS1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated INTS6-AS1 expression acts as an unfavorable survival marker.

SKCM are the cancer types where INTS6-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSMedianAll0.1980.728.01512view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

INTS6-AS1–SKCM (DFS)

Kaplan–Meier survival curve for INTS6-AS1 mutant vs wild-type samples in SKCM.

Open the SKCM breakdown →

Exploration