INTS6-AS1

Across TCGA pan-cancer cohorts, INTS6-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of INTS6-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where INTS6-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types INTS6-AS1 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and LIHC are the cancer types where INTS6-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in INTS6-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.741	<.001	10	view →
KIRP	All	All	−0.272	<.001	9	view →
LIHC	Male	All	+0.231	<.001	8	view →
HNSC	All	All	+0.171	<.001	8	view →
COAD	Male	All	+0.232	<.001	7	view →
UCEC	All	All	−0.461	<.001	6	view →
KIRC	Male	All	−0.141	.010	5	view →
CHOL	All	All	+0.483	.003	4	view →
STAD	All	All	+0.171	.009	4	view →
BRCA	Female	All	−0.155	<.001	4	view →
READ	All	All	+0.418	.020	2	view →
LUSC	All	All	+0.207	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

INTS6-AS1–KICH

Open the KICH breakdown →