INTS6-AS1

Across TCGA pan-cancer cohorts, INTS6-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated INTS6-AS1 data layer compared with 1 for mutation status.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher INTS6-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated INTS6-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and READ show a favorable association.

PAAD, ACC, and COAD are the cancer types where INTS6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Quartile	All	0.589	0.215	<.001	32	view →
ACC	DFS	Quartile	All	0.178	0.765	.008	30	view →
COAD	DFS	Quartile	All	0.683	0.811	.008	29	view →
OV	DFS	Median	II,III,IV	0.334	0.423	.007	20	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	15	view →
LIHC	OS	Quartile	All	0.493	0.686	.009	14	view →
SKCM	DFS	Tertile	IV	0.061	1.000	.024	12	view →
BRCA	DFS	Quartile	IV	0.255	0.828	.008	12	view →
READ	OS	Quartile	II,III,IV	1.000	0.734	.008	12	view →
LUSC	OS	Quartile	All	0.851	0.735	.008	11	view →
LUAD	OS	Quartile	II,III,IV	0.590	0.821	.013	11	view →
KIRC	DFS	Tertile	II,III,IV	0.398	0.613	.023	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

INTS6-AS1–PAAD (OS)

Open the PAAD breakdown →