INSYN2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INSYN2A mutation is significantly associated with the RNA expression of many other genes, with 3,069 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INSYN2A-associated genes across cancer lineages are RNU6-277P, RN7SL488P, and DUX4L19. Each is linked with INSYN2A in more than 2 cancer types. Because this analysis shows association rather than direction, both INSYN2A-to-partner and partner-to-INSYN2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN2A→partner) and Y-score (partner→INSYN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU6-277P →+0.340+4.822<.001.00633
LUSCRN7SL488P →+0.202+4.236<.001.00833
LIHCDUX4L19 →+0.243+5.119<.001.00132
LIHCRN7SL7P →+0.110+5.305<.001.00332
BLCAMIR602 →+0.476+3.788.008.00932
PRADRNU7-52P →+0.503+7.939<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,069 associations by consensus.

Exploration