Q-omics provides the consensus-scored DUX4L19 profile across patient tissues and cancer cell-line models. DUX4L19 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in UCEC. Additionally, DUX4L19 RNA expression shows 5,254 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCEC, and STAD as cancer lineages where DUX4L19 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DUX4L19 survival associations across molecular data types. DUX4L19 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DUX4L19 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	UCEC (72)	view →

This table ranks reproducible DUX4L19 RNA expression–survival associations across cancer types. High DUX4L19 expression shows unfavorable associations in UCEC, KICH, THYM, LAML, PAAD and GBM. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for DUX4L19 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.168	0.742	<.001	72	view →
KICH	OS	Tertile	All	0.439	0.893	<.001	69	view →
THYM	OS	Tertile	All	0.582	0.980	<.001	39	view →
LAML	DFS	Tertile	All	0.203	0.628	<.001	18	view →
PAAD	DFS	Tertile	All	0.198	0.470	.021	18	view →
GBM	DFS	Tertile	All	0.048	0.242	.006	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

DUX4L19-UCEC (DFS)

Kaplan–Meier survival curve for DUX4L19 RNA expression in UCEC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DUX4L19 in patient tissues and cancer cell lines. In patient samples, DUX4L19 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,254	STAD (5052)	view →
RNA	3,009	ESCA (890)	view →