INSM1

Across TCGA patient cohorts, INSM1 mutation is significantly associated with the RNA expression of many other genes, with 1,229 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INSM1-associated genes across cancer lineages are RNU6-32P, MIR3168, and CHORDC1P5. Each is linked with INSM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both INSM1-to-partner and partner-to-INSM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-32P grouped by INSM1-low versus INSM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSM1→partner) and Y-score (partner→INSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-32P →	+0.523	+2.081	<.001	.003	3	3
LIHC	MIR3168 →	+0.366	+4.308	.009	.007	3	2
LIHC	CHORDC1P5 →	+0.061	+5.066	<.001	.001	3	2
UCEC	RNA5SP351 →	+0.368	+2.298	<.001	.002	3	2
COAD	RNU6-918P →	+0.326	+5.392	<.001	.002	3	2
COAD	VN1R37P →	+0.067	+5.917	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,229 associations by consensus.

RNU6-32P by INSM1 expression — UCEC

Explore this box plot interactively →