Q-omics provides the consensus-scored ILDR1 profile across patient tissues and cancer cell-line models. ILDR1 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, ILDR1 is differentially expressed in 12, with the highest sampling consensus in KIRC. Additionally, ILDR1 RNA expression shows 17,404 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight KIRC, and KIRP as cancer lineages where ILDR1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ILDR1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ILDR1 survival associations across molecular data types. ILDR1 RNA expression shows survival associations in the most cancer types (18), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ILDR1 RNA expression–survival associations across cancer types. High ILDR1 expression shows unfavorable associations in LGG, but favorable associations in KIRC, MESO, READ, SKCM and UCEC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for ILDR1 RNA expression.
This table summarizes ILDR1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12, while mass-spec protein shows differences in 1. The strongest signals are observed in KIRC for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for ILDR1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ILDR1 shows lower tumor expression in KIRC and KIRP and higher tumor expression in STAD, BRCA, CHOL and BLCA. The KIRC box plot shows higher ILDR1 RNA expression in normal versus tumor tissue (log2 FC = −2.021, t-test p < 0.001).
This table shows molecular features associated with ILDR1 in patient tissues and cancer cell lines. In patient samples, ILDR1 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set. In cancer cell lines, ILDR1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Lymphoma and LUNG_SCLC.
